{"created":"2023-06-28T07:20:35.558748+00:00","id":55,"links":{},"metadata":{"_buckets":{"deposit":"5cf7d98f-ef75-45e8-92ff-13d08a69ec19"},"_deposit":{"created_by":2,"id":"55","owners":[2],"pid":{"revision_id":0,"type":"depid","value":"55"},"status":"published"},"_oai":{"id":"oai:gchs.repo.nii.ac.jp:00000055","sets":["10:11:17"]},"author_link":["436","435","433","434"],"item_3_alternative_title_12":{"attribute_name":"その他のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"Asymmetric Distribution of Filament Bundles in Smooth Muscle Cells and Fibronectin Distribution Pattern in Extracellular Space of Chick Embryonic Arteries"}]},"item_3_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2011-03","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"19","bibliographicPageStart":"13","bibliographicVolumeNumber":"6","bibliographic_titles":[{"bibliographic_title":"群馬県立県民健康科学大学紀要"}]}]},"item_3_description_14":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"Article","subitem_description_type":"Other"}]},"item_3_description_3":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"ふ卵5日目から20日目のニワトリ胚動脈の中膜平滑筋における収縮性線維束の分布と細胞外のフィブロネクチン分布様式との関係を,電子顕微鏡と蛍光染色法によって調べた.5日目から17日目胚の平滑筋では,アクチン線維を含む線維束が細胞長軸に沿って伸びるとともに,内皮側に偏って位置していた.平滑筋の線維束が細胞膜に付着する場所の外側には細胞外の微細線維も付着していたが,この微細線維は中膜全体ではほぼ均一に分布した.細胞外の線維構造に含まれるフィブロネクチン分布を蛍光抗体法で調べると,ふ卵20日目までの発育過程全期間を通じてフィブロネクチン束は中膜内で立体的な網目状をなし,平滑筋はこの網の中にあった.以上の結果から,平滑筋内における線維束の一時的な偏在は,細胞外のフィブロネクチン束の分布様式とは関連が低いものと考えられた.細胞外の線維構造が少ない若い胚の中膜平滑筋でも,収縮性線維束が内皮側すなはち細胞内の管腔側で形成され始めることから,この線維束の細胞内分布は血流によって影響されることが示唆された.","subitem_description_type":"Abstract"},{"subitem_description":"The distribution pattern of the contractile filament bundle in smooth muscle cells and fibronectin fibrils in extracellular space were studied in chick embryonic arteries. Arteries obtained from embryos from 5 to 20 days in ovo were examined with electron microscopy and histochemistry using rhodamine-labeled phalloidin and anti-fibronectin IgG. Actin-containing filament bundles were present predominantly in cytoplasmic areas below the luminal end of smooth muscle cells in embryos younger than 17 days. These bundles became thick and were distributed uniformly through the cell body of muscle during embryonic development. Immunofluorescent staining with anti-fibronectin IgG showed a mesh-like pattern in the matrix of the arterial media during whole embryonic stages. The pattern of actin-containing filament bundles and fibronectin fibrils were also observed in small branches of arteries. Morphological results suggest that fibronectin distribution may not play a decisive role in inducing luminal side localization of contractile filament bundles in developing smooth muscle cells.","subitem_description_type":"Abstract"}]},"item_3_description_4":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"原著","subitem_description_type":"Other"}]},"item_3_description_5":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"群馬県立県民健康科学大学紀要 6,13-19,2011","subitem_description_type":"Other"}]},"item_3_publisher_13":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"群馬県立県民健康科学大学"}]},"item_3_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1881-0691","subitem_source_identifier_type":"ISSN"}]},"item_3_source_id_8":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA12136570","subitem_source_identifier_type":"NCID"}]},"item_3_version_type_10":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"神宮司, 洋一"}],"nameIdentifiers":[{"nameIdentifier":"433","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"田中, 秀幸"}],"nameIdentifiers":[{"nameIdentifier":"434","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Jinguji, Yoichi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"435","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Tanaka, Hideyuki","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"436","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2021-03-09"}],"displaytype":"detail","filename":"KJ00006924945.pdf","filesize":[{"value":"1.9 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"KJ00006924945.pdf","url":"https://gchs.repo.nii.ac.jp/record/55/files/KJ00006924945.pdf"},"version_id":"788fe7e0-1d84-4357-b09e-0a19e45f9e99"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"ニワトリ胚","subitem_subject_scheme":"Other"},{"subitem_subject":"動脈平滑筋","subitem_subject_scheme":"Other"},{"subitem_subject":"収縮性線維束","subitem_subject_scheme":"Other"},{"subitem_subject":"フィブロネクチン","subitem_subject_scheme":"Other"},{"subitem_subject":"chick embryo","subitem_subject_scheme":"Other"},{"subitem_subject":"arterial smooth muscle","subitem_subject_scheme":"Other"},{"subitem_subject":"contractile filament bundle","subitem_subject_scheme":"Other"},{"subitem_subject":"fibronectin","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"ニワトリ胚動脈平滑筋の収縮性線維束の偏在と細胞外線維構造におけるフィブロネクチン分布","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"ニワトリ胚動脈平滑筋の収縮性線維束の偏在と細胞外線維構造におけるフィブロネクチン分布"}]},"item_type_id":"3","owner":"2","path":["17"],"pubdate":{"attribute_name":"公開日","attribute_value":"2012-02-17"},"publish_date":"2012-02-17","publish_status":"0","recid":"55","relation_version_is_last":true,"title":["ニワトリ胚動脈平滑筋の収縮性線維束の偏在と細胞外線維構造におけるフィブロネクチン分布"],"weko_creator_id":"2","weko_shared_id":-1},"updated":"2023-06-28T07:25:15.199066+00:00"}